Abstract
A reliable and modified protocol based on the CTAB method was developed for DNA extraction from old needles of Cedrus deodara (Roxb.) G.Don. The presence of high concentrations of polysaccharides, polyphenols and other secondary metabolites in C. deodara needles poses problem in getting good quality DNA fit for PCR applications. used 2.5% PVP for removal of phenolics compound and apply high concentration of sodium chloride to removes polysaccharides. Oils was removed by centrifugation. The yield of extracted DNA was ranged from 35 to 130 µg/100mg fresh weight of the needles with absorbance ratio (A260/A280) ranged from 1.82 to 2.0. DNA extracted by modified protocol gives positive amplification with PCR using Nuclear Simple Sequence Repeat (SSR) markers. This modified protocol can be used in genomic DNA extraction from closely related species of C. deodara.
Keywords
CTAB, Nuclear Simple Sequence Repeat (SSR), DNA extraction, PCR application, Cedrus deodara (Roxb.) G.Don Needles